Structure Information

PDB: 9NA3
Resolution: 2.10 Å
Method: X-ray diffraction
Organism: Homo sapiens

Publication

Discovery of Edecesertib (GS-5718): A Potent, Selective Inhibitor of IRAK4.

Ammann, S.E., Cottell, J.J., Wright, N.E., Warr, M.R., Snyder, C.A., Bacon, E.M., Brizgys, G., Chin, E., Chou, C., Conway, A., Dick, R.A., Ferrao, R.D., Garrison, K.L., Hammond, A., Lansdon, E.B., Link, J.O., Mukherjee, P.K., Murray, B.P., Mwangi, J., Ndukwe, M.S., Park, G.Y., Serone, A.P., Suekawa-Pirrone, K., Yang, Z.Y., Zipfel, S.M., Taylor, J.G. (2025) J Med Chem 68: 10619-10630
DOI: https://doi.org/10.1021/acs.jmedchem.5c00463